07.00 - 08.45 - Breakfast

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09.00 - 19.00 - Registration

 

09.00 - Symposium 2

SPERMATOGONIAL STEM CELLS

Chairpersons: Jon Oatley, Elena Vicini & Stefan Schlatt

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09.00 - 09.30 - Shosei Yoshida - Flexible and stochastic behavior of spermatogenic stem cells
09.30 - 10.00 - Miles Wilkinson - Spermatogonial Stem Cell Establishment

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Miniposter Session 2

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10.00 - Selected miniposters

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10.00 - 10.15 - Geoffrey Maher, Hannah Ralph, Zhihao Ding, Nils Koelling, Hana Mlcochova, Pawan Dhami, Eleni Giannoulatou, Gilean McVean, Andrew Wilkie and Anne Goriely - Assessing the landscape of selfish de novo mutations in human testes

10.15 - 10.30 - Juho-Antti Mäkelä, Hue La, Ai-Leen Chan, Fernando Rossello, Christian Nefzger, Mia De Seram, Jose Polo and Robin Hobbs - Genetic control of male germline stem and progenitor cell heterogeneity and fate

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10.30 - 10.45  – Michela Ciccarelli, Mariana Giassetti and Jon Oatley – Regeneration of spermatogenesis in
Sertoli-cell-only NANOS2 knockout pigs by homologous spermatogonial stem cell transplantation

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10.45 - Coffee break

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11.15 - 11.50 - Short talks

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Tessa Lord, Melissa Oatley, Deqiang Miao and Jon Oatley - Identification of novel testis-specific transcription factors that regulate spermatogonial stem cell maintenance using a large-scale siRNA screen

Reza Shirazi and Iraj Kashani - Generation of male germ cells from pluripotent stem cells derived from an adult tissue

Alaa Sawaied, Natalie Geller, Eitan Lunenfeld and Mahmoud Huleihel - Interleukin-34 is a novel testicular factor that induced proliferation, meiotic and postmeiotic stages of immature mouse spermatogonial cells in vitro

Noy Bagdadi, Eitan Lunenfeld and Mahmoud Huleihel - Possible involvement of pigment epithelium derived factor (PEDF) in the proliferation and differentiation of immature mouse spermatogonial cells in vitro

Eva Wolff and Rüdiger Behr - Primordial germ cell culture of the common marmoset monkey

Maria Sousa, Ana Rodrigues, Bibiana Correia, João Ramalho-Santos - A novel pluripotent-paused state

Stephen Frankenberg, Micaela Sood and Andrew Pask - Isolation and characterisation of spermatogonial stem cells from a marsupial, the fat-tailed dunnart

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12.00 - Lunch

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13.15 - Symposium 3

SOMATIC CELLS & SPERMATOGENESIS

Chairpersons: Lee Smith, Katja Teerds & Paula Mota

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13.15 - 13.45 - Mario Ascoli - The roles of the ERK1/2 cascade on the Proliferation and differentiation of Leydig cells
13.45 - 14.15 - Luiz França - Sertoli cells (plasticity, function, interaction with germ cells, differences among species)

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Miniposter Session 3

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14.15 - Selected miniposters

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14.15 - 14.30 - Eva Pohl, Joachim Wistuba, Sabine Kliesch and Jörg Gromoll - Effects of ageing on the testis - Constant spermatogenic output appears to be maintained by enhanced spermatogonial proliferation in elderly men 

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14.30 - 14.45 - Yasmine Neirijnck, Pierre Calvel, Karen Kilcoyne, Françoise Kühne, Isabelle Stévant, Richard Griffeth, Jean-Luc Pitetti, Silvana Andric, Meng-Chun Hu, François Pralong, Lee Smith and Serge Nef - Insulin and IGF1 receptors are essential for the development and steroidogenic function of adult Leydig cells

14.45 - 15.40 - Short talks I

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Shishir Patel and Shio Singh - Pyroglutamylated RFamide peptide (QRFP): Role in regulation of spermatogenesis in relation to energy metabolism

Tao Lei, Nancy Freitag, Yahia Almousa, Martin Bergmann, Sudhanshu Bhushan, Annie Huang, Hung-Lin Chen, Fu-Tong Liu, Sandra Blois, Andreas Meinhardt and Monika Fijak - Mice deficient for galectin 3 display disturbed maturation of Sertoli cells, delay of the first wave of spermatogenesis and increased apoptosis of germ cells

Michael Curley, Laura Milne, Sarah Smith, Nina Atanassova, Diane Rebourcet, Annalucia Darbey, Patrick Hadoke, Sara Wells and Lee Smith - Leukemia inhibitory factor receptor is required in Sertoli Cells but not germ cells to maintain normal spermatogenic function in mice

Agnieszka Milon, Piotr Pawlicki, Jerzy Galas, Alicja Kaminska, Laura Pardyak, Klaudia Lesniak, Anna Pacwa, Barbara Bilinska, Ewelina Gorowska-Wojtowicz and Malgorzata Kotula-Balak - Role of estrogen-related receptors in bank vole Leydig cell function

Malgorzata Kotula-Balak, Barbara Bilinska, Piotr Pawlicki, Agnieszka Milon, Patrycja Dutka, Maja Kudrycka, Malgorzata Sekula, Anna Hejmej and Ewelina Gorowska-Wojtowicz - Do estrogen-related receptors regulate tumor mouse Leydig cells?

Christiane Pleuger, Madeleine Cooper, Daniela Fietz, Mark Baker, Hans-Christian Schuppe, Wolfgang Weidner, Sabine Kliesch, Moira O'Bryan and Martin Bergmann - The role of the cilia-related CBE1 (ciliated bronchial epithelium 1) in spermatogenesis

David Fleck, Justine Fischoeder, Naofumi Uesaka and Marc Spehr - Visualization of spontaneous Ca2+ signals in intact mouse Sertoli cells

Marie-Justine Guerquin, Justine Galissant, Aurélie Chaulot-Talmon, Michele Darmon, Justine Masson, Jorge Diaz, Virginie Rouiller-Fabre and Gabriel Livera - Yif1b is essential for male fertility in mouse

Alberto De La Iglesia, Ferran Barrachina, Judit Castillo, Afsaneh Goudarzi, Sophie Rousseaux, Saadi Kochbin, Carme Mallofré, Leonardo Rodríguez-Carunchio, Josep Ballescà and Rafael Oliva - Characterizing H4K5bu in human spermatogenesis and testicular pathologies as a new acylation modulating the chromatin state

Valentina Mularoni, Valentina Esposito, Flaminia Fanelli, Sara Di Persio, Rossana Saracino, Elena Vicini and Carla Boitani - Changes in Leydig cell number and function during aging in men

Nadege Vernet, Marius Teletin, Betty Feret, Muriel Klopfenstein, Sirine Souali-Crespo, Maureen Kane, Norbert Ghyselinck and Manuel Mark - Redundant function of RALDH1 and RALDH2 in the seminiferous epithelium

 

15.40 - Coffee Break

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16.10 - 17.15 - Short talks II

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Sheyla Cisneros-Montalvo, Emmi Lokka, Juho-Antti Mäkelä, Mirja Nurmio, Jorma Toppari, Marko Salmi and Pia Rantakari - The role of PLVAP in testis development and spermatogenesis 

Igor Tomczyk, Bernadeta Pawlicka, Agneta Auer, Katarzyna Rożek and Paweł Grzmil - PXT1 and BAG6 interplay in the control of sperm quality in mouse

Sara Di Persio, Rossana Saracino, Stefania Fera and Elena Vicini - Retinoic acid regulation of human spermatogonial genes

Karen Kilcoyne, Cornelia Roesl, Annalucia Darbey, Hazel Stewart, Laura Milne, Rod Mitchell, Richard Mellanby, Pamela Brown and Lee Smith - Development of a single injection non-surgical sterilant via androgen receptor targeting

Lucía Martínez-Fresneda, Dawit Tesfaye, Karl Schellander, Francisco García-Vázquez and Julian Santiago-Moreno - Seasonal variations of the seminiferous tubules morphometry in domestic rams (Ovis aries)

Marion Delessard, Côme Ialy-Radio, Mélina Blanco, Charlotte Moretti and Julie Cocquet - Male germ cell knockout of the histone methyl transferase Dot1l leads to multiple defects during spermatogenesis

Katja Hartmann, Sabine Kliesch, Florian Wagenlehner, Martin Bergmann and Daniela Fietz - Membrane-bound steroid hormone-receptors and their expression pattern in the testis of humans and different domesticated species

Judit Castillo, Orleigh Bogle, Carme Mallofré, Josep Ballescà and Rafael Oliva - Characterization of the histone lysine demethylase PHF8 during human spermatogenesis

Margareeta Mäkelä, Tiina Lehtiniemi, Fuping Zhang and Noora Kotaja - SMG6 endonuclease is essential for spermatogenesis in mice

Fei Sun - Nano contraception

Rossana Saracino, Sara Di Persio, Stefania Fera and Elena Vicini - Retinoic acid down-regulates GDNF expression in immature Sertoli cells

Bushra Dohai, Amphun Chaiboonchoe, Erwin Goldberg and Kourosh Salehi-Ashtiani - Metabolic properties of mouse spermatogenesis defined through constraint-based modeling

Matteo Da Ros, Tiina Lehtiniemi, Oliver Meikar, Opeyemi Olotu and Noora Kotaja - Simple protocol to enrich spermatocytes and spermatids from mouse testes using standard laboratory equipment

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17.15 - Break

 

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17.45 - Symposium 4

MALE REPRODUCTIVE TRACT: DUCTS AND ACCESSORY GLANDS 

Chairpersons: Andreas Meinhardt, Ralph Middendorff & Alexandra Amaral

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17.45 - 18.15 - Sylvie Breton - Extracellular communication networks in the epididymis: impact on optimal environment for sperm maturation 
18.15 - 18.45 - Petra Sipilä - Epididymal gene expression: impact on sperm maturation

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Miniposter Session 4

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18.45 - Selected miniposters

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18.45 - 19.00 - Ferran Barrachina, Meritxell Jodar, Ada Soler-Ventura, Josep Estanyol, Juan Corral, Josep Ballescà and Rafael Oliva - The protein abundance from the male reproductive tract secretions may be regulated by the sperm presence

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19.00 - 19.15 – Giulia Matusali, Anne-Pascale Satie, Florence Aubry, Dominique Mahé, Laurent Houzet,
Julie Frouard, Salomé Bourgeau, Karim Bensalah, Christian Platel, Anna Le Tortorec and Nathalie Dejucq-
Rainsford – Zika virus replicates within the human testis and infects somatic cells and germ cells

 

20.00 - Dinner