14.00 - 19.00 - Arrival and Registration

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16.00 - 16.15 - Welcome

João Ramalho-Santos & Sandra Amaral

 

16.15 - Symposium 1

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ENDOCRINOLOGY, SEX DETERMINATION & DEVELOPMENT

Chairpersons: Serge Nef, Anne Jørgensen & Ana Paula Sousa

 

16.15 - 16.45 - Anu Bashamboo -  Mechanisms of sex determination

16.45 - 17.15 - Robin Lovell-Badge - Sox 9 and sex determination

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17.15 - 17.30 - Coffee Break

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Miniposter Session 1

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17.30 - 18.00 - Selected posters

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17.15 - 17.30

Pedro Prudêncio, Leonardo Guilgur, João Sobral, Jörg Becker, Rui Martinho and Paulo Navarro-Costa - The unpacking of the sperm genome after fertilization requires the dMLL3/4 chromatin regulator

17.30 - 17.45

Aurélie Lardenois, Bertrand Evrard, Séverine Mazaud-Guittot, Laurianne Lesné, Bernard Jégou, Frédéric Chalmel and Antoine Rolland - Characterization of the expression program underlying rat testis differentiation at the single cell level

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18.00 - 19.00 - Short talks

 

Iuliia Savchuk, Olle Söder and Konstantin Svechnikov - Steroidogenesis in human fetal testes in the first trimester of pregnancy

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Stefan Bagheri-Fam, Katie Ayers, Raphael Rastetter, Paul Thomas, Andrew Sinclair, Juan Pié, Serge Nef and Dagmar Wilhelm - New pathway involved in 46,XY disorders of sex development

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Deidre Mattiske and Andrew Pask - Oestrogen regulates key developmental pathways in somatic cells of the gonad

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Melanie Stewart, Deidre Mattiske and Andrew Pask - Oestrogen blocks the nuclear translocation of SOX9 in the human Sertoli-like cell line NT2/D1

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Cecilie Melau, John Nielsen, Hanne Frederiksen, Anna-Maria Andersson, Rod Mitchell, Anders Juul and Anne Jørgensen  - Steroidogenic activity of the human fetal adrenal gland

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Isabelle Stévant, Yasmine Neirijnck, Emmanouil Dermitzakis and Serge Nef - Reconstructing gonadal sex fate decision using single-cell RNA-seq

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Isabelle Stévant, Pauline Sararols, Yasmine Neirijnck, Diane Rebourcet, Lee Smith and Serge Nef - Identification of discriminant marker genes between fetal and adult Leydig cells

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Camilla Schwartz, Anne Vingaard, Sofie Christiansen, Frederic Chalmel and Terje Svingen - Characterizing novel molecular mechanisms for short AGD - A biomarker of fetal testicular dysfunction

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Jitske Eliveld, Eva Van Den Berg, Fulco Van Der Veen, Sjoerd Repping, Katja Teerds and Ans Van Pelt - Human testicular PDGFRa+ cells can differentiate into cells with Leydig cell characteristics

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Sirine Souali-Crespo, Nedege Vernet, Manuel Mark and Norbert Ghyselinck - Role of SF1 in embryonic Sertoli cells in mice

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Jinfei Yang - A new strategy for the synthesis of reproductive medicine

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Ahmed Bulldan, Georgios Scheiner-Bobis and Lutz Konrad - Physiological and pathophysiological relevance of ZIP9, a zinc transporter, androgen receptor, and G-protein-coupled signal transducer

 

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19.00 - 19.45 - Plenary session

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Ilpo Huhtaniemi - Unravelling secrets of the pituitary-testicular axis

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20.30 - Dinner